Prolific source rocks, an abundance of trap types and stacked reservoirs and seals combine to make the Gulf of Mexico (GOM) a hydrocarbon super-basin. The GOM was the main site of development of sequence stratigraphy and seismic sequence stratigraphy. That work was concentrated in the northern half of the GOM. Less work was published on the southern half of the GOM. We present here a completed stratigraphic model for the Mexican Gulf of Mexico (MGOM) built using interpreted well and seismic data from Middle Jurassic to Quaternary. For 201 key wells we interpreted lithology, sequences to 2nd and 3rd order level and all the chronostratigraphic and lithostratigraphic units. From this information we derived the geological environment of deposition and associated depositional facies. 18 geological and depositional environment (facies) maps were created for key sequences across the MGOM – to provide a composite regional stratigraphic framework that is representative of the sub-basins in the MGOM.